Recombinant Pepsinogen II (PGII) Antibody

    应用:
  • CLIA
  • Detection Antibody
  • ELISA
功能和特点
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: 34G7
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
Ab007790-10μg
10μg 现货 Stock Image
Ab007790-50μg
50μg 现货 Stock Image
Ab007790-100μg
100μg 现货 Stock Image
Ab007790-1mg
1mg 期货 Stock Image

基本信息

产品名称 Recombinant Pepsinogen II (PGII) Antibody
别名 重组胃蛋白酶原 II (PGII) 抗体
英文别名 EC 3.4.23.3 | Pepsinogen C
规格或纯度 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属 小鼠(Mouse)
特异性 PGII
应用 ELISA,CLIA,Detection antibody
种属反应性 人(Human)
免疫原 E. coli-derived recombinant human PGII
偶联 Unconjugated

产品属性

抗体类型 Primary antibody
克隆类型 重组抗体
克隆号 34G7
Format Whole IgG
亚型 IgG1
SDS-PAGE 150 kDa
纯化方法 Protein A purified
配对抗体 [Ab007791] Recombinant Pepsinogen II (PGII) antibody as Capture antibody
来源 CHO supernatant
物理外观 Liquid
储存缓冲液 10mM PB+150mM NaCl+ 0.1% ProClin300, pH6.0
防腐剂 0.1% ProClin 300
浓度 见COA
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Storage: -20℃ for long term storage. Avoid repeated freeze/thaw cycles.
分子类型 抗体

图片

Relevance of detection results between aladdin Antibody Pair (Ab007791 & Ab007790) and Abbott in CLIA
· Capture antibody: Recombinant Pepsinogen II (PGII) Antibody (Ab007791) at 1.0 μg/mL.
· Detection antibody: Recombinant Pepsinogen II (PGII) Antibody (Ab007790) at 1.0 μg/mL.
· Linear Range: 0.5-100 ng/mL, R² ≥ 0.95.

关联靶点(人)

PGC Tchem 胃泌素(Gastricsin) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

质量标准

应用

应用名称 稀释比例
ELISA

1 μg/mL

CLIA

1 μg/mL

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1012178 分析证书 24-10-16 Ab007790
ZJ23F0600302 分析证书 23-06-13 Ab007790
ZJ23F0600303 分析证书 23-06-13 Ab007790

参考文献

1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P et al..  (2004)  The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)..  Genome Res,  14  (10B): (2121-7).  [PMID:15489334]
2. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al..  (2004)  Complete sequencing and characterization of 21,243 full-length human cDNAs..  Nat Genet,  36  (1): (40-5).  [PMID:14702039]
3. Ostermann N, Ruedisser S, Ehrhardt C, Breitenstein W, Marzinzik A, Jacoby E, Vangrevelinghe E, Ottl J, Klumpp M, Hartwieg JC, Cumin F, Hassiepen U, Trappe J, Sedrani R, Geisse S, Gerhartz B, Richert P, Francotte E, Wagner T, Krömer M, Kosaka T, Webb RL, Rigel DF, Maibaum J, Baeschlin DK..  (2013)  A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore..  J Med Chem,  56  (6): (2196-2206).  [PMID:23360239] [10.1021/jm301706j]
4. Sellner H, Cottens S, Cumin F, Ehrhardt C, Kosaka T, Lorthiois E, Ostermann N, Webb RL, Rigel DF, Wagner T, Maibaum J..  (2015)  trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linker..  Bioorg Med Chem Lett,  25  (8): (1787-1791).  [PMID:25754490] [10.1016/j.bmcl.2015.02.040]
5. Athauda, S B SB, Tanji, M M, Kageyama, T T and Takahashi, K K..  (1989)  A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins..  Journal of biochemistry,  [PMID:2515193]
6. Pals, G G and 8 more authors..  (1989)  Human pepsinogen C (progastricsin) polymorphism: evidence for a single locus located at 6p21.1-pter..  Genomics,  [PMID:2567697]
7. Taggart, R T RT and 6 more authors..  (1989)  Human pepsinogen C (progastricsin). Isolation of cDNA clones, localization to chromosome 6, and sequence homology with pepsinogen A..  The Journal of biological chemistry,  (5): [PMID:2909526]
8. Hayano, T T, Sogawa, K K, Ichihara, Y Y, Fujii-Kuriyama, Y Y and Takahashi, K K..  (1988)  Primary structure of human pepsinogen C gene..  The Journal of biological chemistry,  (25): [PMID:3335549]
9. Foltmann, B B and Jensen, A L AL..  (1982)  Human progastricsin. Analysis of intermediates during activation into gastricsin and determination of the amino acid sequence of the propart..  European journal of biochemistry,  [PMID:6816595]
10. Moore, S A SA, Sielecki, A R AR, Chernaia, M M MM, Tarasova, N I NI and James, M N MN..  (1995)  Crystal and molecular structures of human progastricsin at 1.62 A resolution..  Journal of molecular biology,  (31): [PMID:7714902]
11. Khan, A R AR, Cherney, M M MM, Tarasova, N I NI and James, M N MN..  (1997)  Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin..  Nature structural biology,  [PMID:9406551]
12. Mungall, A J AJ and 170 more authors..  (2003)  The DNA sequence and analysis of human chromosome 6..  Nature,  (23): [PMID:14574404]

溶液计算器