| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab005524-10μg |
10μg |
现货  |
| |
| Ab005524-50μg |
50μg |
现货 |
| |
| Ab005524-100μg |
100μg |
现货 |
| |
| Ab005524-1mg |
1mg |
期货 |
|
| 产品名称 | CA125 Mouse mAb |
|---|---|
| 别名 | CA125小鼠单克隆抗体 | CA125小鼠单抗 |
| 英文别名 | CA-125 | MUC-16 | Ovarian cancer-related tumor marker CA125 | Ovarian carcinoma antigen CA125 |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | Antibody recognizes human cancer antigen 125 (CA125) |
| 应用 | ELISA,CLIA |
| 种属反应性 | 人(Human) |
| 免疫原 | E. coli-derived recombinant human CA125 |
| 表位 | DomainA（表位类M11） |
| 偶联 | Unconjugated |
| 抗体类型 | Primary antibody |
|---|---|
| 克隆类型 | 单克隆抗体 |
| 克隆号 | 4F8 |
| Format | Whole IgG |
| 亚型 | IgG2a |
| 离解常数（KD） | Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. |
| 纯化方法 | Protein A purified |
| 配对抗体 | [Ab005528] CA125 Mouse mAb as capture antibody in ELISA, CLIA. |
| 来源 | Hybridoma supernatant |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PB+150mM NaCl+0.1% Proclin 300，pH7.4 |
| 防腐剂 | 0.1% Proclin 300 |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | Storage: -20℃ for long term storage. Avoid repeated freeze / thaw cycles. |
| 分子类型 | 抗体 |
Relevance of detection results between aladdin Antibody Pair (Ab005528 & Ab005524) and Roche in CLIA
· Capture antibody: CA125 Mouse mAb (Ab005528) at 1.0 μg/mL.
· Detection antibody: CA125 Mouse mAb (Ab005524) at 1.0 μg/mL.
· Linear Range: 0.6-5000 U/mL, R2 ≥ 0.98.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 应用名称 | 稀释比例 |
|---|---|
| ELISA |
1 μg/mL |
| CLIA |
1 μg/mL
|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F1012074 |
分析证书 | 24-10-14 | Ab005524 |
| ZJ23F0500247 |
分析证书 | 23-06-05 | Ab005524 |
| ZJ23F0500249 |
分析证书 | 23-06-05 | Ab005524 |
¥969.90
¥999.90
| 1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al.. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs.. Nat Genet, 36 (1): (40-5). [PMID:14702039] |
| 2. Yin, B W BW and Lloyd, K O KO.. (2001) Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16.. The Journal of biological chemistry, (20): [PMID:11369781] |
| 3. O'Brien, T J TJ and 5 more authors.. The CA 125 gene: an extracellular superstructure dominated by repeat sequences.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, [PMID:11786729] |
| 4. O'Brien, Timothy J TJ, Beard, John B JB, Underwood, Lowell J LJ and Shigemasa, Kazushi K.. The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, [PMID:12218296] |
| 5. Kui Wong, Nyet N and 9 more authors.. (2003) Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125.. The Journal of biological chemistry, (1): [PMID:12734200] |
| 6. Rump, Armin A and 6 more authors.. (2004) Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.. The Journal of biological chemistry, (5): [PMID:14676194] |
| 7. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824] |
| 8. McLemore, Monica R MR and Aouizerat, Bradley B.. (2005) Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer.. Biological research for nursing, [PMID:15788735] |
| 9. Argüeso, Pablo P, Tisdale, Ann A, Spurr-Michaud, Sandra S, Sumiyoshi, Mika M and Gipson, Ilene K IK.. (2006) Mucin characteristics of human corneal-limbal epithelial cells that exclude the rose bengal anionic dye.. Investigative ophthalmology & visual science, [PMID:16384952] |
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