货号 (SKU)

包装规格

是否现货

价格

数量

Ab005500-10μg

10μg

现货

Ab005500-50μg

50μg

现货

Ab005500-100μg

100μg

现货

Ab005500-1mg

1mg

期货

基本信息

产品名称	Recombinant Troponin I/TNNI3 Antibody
别名	重组肌钙蛋白 I/TNNI3 抗体
英文别名	Cardiac troponin I
规格或纯度	无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
应用	Detection antibody in GICA/LF,Capture antibody in FIA
种属反应性	人(Human)
免疫原	E. coli-derived recombinant human CTNI
表位	24-40 aa
偶联	Unconjugated

产品属性

抗体类型	Primary antibody
克隆类型	重组抗体
克隆号	23C12
Format	Whole IgG
亚型	IgG1
SDS-PAGE	150 kDa
纯化方法	Protein A purified
配对抗体	[Ab005432] Recombinant Troponin I/TNNI3 antibody as Detection antibody in CLIA, ELISA; [Ab005499] Recombinant Troponin I/TNNI3 antibody as Capture antibody in LF/GICA; [Ab005751] Recombinant Troponin I/TNNI3 antibody as Capture antibody in LF/GICA; [Ab00
来源	CHO supernatant
物理外观	Liquid
储存缓冲液	10mM PB+150mM NaCl+0.1% ProClin 300，pH7.4
防腐剂	0.1% ProClin 300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Storage: -20℃ for long term storage. Avoid repeated freeze/thaw cycles.
分子类型	抗体

图片

Binding ELISA: Recombinant Troponin I/TNNI3 Antibody (Ab005500)

Recombinant Troponin I/TNNI3 Antibody (Ab005500)-Binding ELISA
The binding activity of recombinant Troponin I/TNNI3 antibody with Troponin I/TNNI3 antigen.

Troponin I/TNNI3 Standard Curve with Antibody Pair (Ab005500 & Ab005432) in CLIA

Troponin I/TNNI3 Standard Curve with Antibody Pair (Ab005500 & Ab005432) in CLIA

· Capture antibody: Recombinant Troponin I/TNNI3 Antibody (Ab005500) at 1.0 μg/mL.

· Detection antibody: Recombinant Troponin I/TNNI3 Antibody (Ab005432) at 1.0 μg/mL.

· Linear Range: 0-35000 pg/mL, R ≥ 0.99.

Troponin I/TNNI3 Standard Curve with Antibody Pair (Ab005499 & Ab005748 & Ab005751 & Ab005500) in GICA

Troponin I/TNNI3 Standard Curve with Antibody Pair (Ab005499 & Ab005748 & Ab005751 & Ab005500) in GICA

· Capture antibody: Recombinant Troponin I/TNNI3 Antibody (Ab005499 & Ab005748 & Ab005751) at 1.0 mg/mL.

· Detection antibody: Recombinant Troponin I/TNNI3 Antibody (Ab005500) at 1.0 mg/mL.

· Linear Range: 0.08-100 ng/mL, LLOD: 0.08 ng/mL.

关联靶点（人）

TNNI3 Tbio 肌钙蛋白 I，心肌(Troponin I, cardiac muscle) (0 活性数据)

点击查看靶蛋白信息： TNNI3

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

安全和危险性（GHS）

SDS英文版

质量标准

质量标准

应用

应用名称	稀释比例
ELISA	1 μg/mL
CLIA	1 μg/mL
LF/GICA	0.4-1.0mg/mL

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	日期	货号
ZJ24F1011955	分析证书	24-10-12	Ab005500
ZJ23F0500256	分析证书	23-06-02	Ab005500
ZJ23F0500257	分析证书	23-06-02	Ab005500

可替换产品

参考文献

1. Hunkeler, N M NM, Kullman, J J and Murphy, A M AM.. (1991) Troponin I isoform expression in human heart.. Circulation research, [PMID:1934363]
2. Vallins, W J WJ and 5 more authors.. (1990) Molecular cloning of human cardiac troponin I using polymerase chain reaction.. FEBS letters, (17): [PMID:2226790]
3. Mittmann, K K, Jaquet, K K and Heilmeyer, L M LM.. (1990) A common motif of two adjacent phosphoserines in bovine, rabbit and human cardiac troponin I.. FEBS letters, (29): [PMID:2226863]
4. Armour, K L KL, Harris, W J WJ and Tempest, P R PR.. (1993) Cloning and expression in Escherichia coli of the cDNA encoding human cardiac troponin I.. Gene, (15): [PMID:8406024]
5. Bhavsar, P K PK, Brand, N J NJ, Yacoub, M H MH and Barton, P J PJ.. (1996) Isolation and characterization of the human cardiac troponin I gene (TNNI3).. Genomics, (1): [PMID:8661099]
6. Kimura, A A and 23 more authors.. (1997) Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.. Nature genetics, [PMID:9241277]
7. Keane, N E NE and 5 more authors.. (1997) The ordered phosphorylation of cardiac troponin I by the cAMP-dependent protein kinase--structural consequences and functional implications.. European journal of biochemistry, (1): [PMID:9346285]
8. Li, M X MX, Spyracopoulos, L L and Sykes, B D BD.. (1999) Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C.. Biochemistry, (29): [PMID:10387074]
9. Niimura, Hideshi H and 6 more authors.. (2002) Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.. Circulation, (29): [PMID:11815426]
10. Wang, Xu X, Li, Monica X MX and Sykes, Brian D BD.. (2002) Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil.. The Journal of biological chemistry, (23): [PMID:12060657]
11. Buscemi, Nina N, Foster, D Brian DB, Neverova, Irina I and Van Eyk, Jennifer E JE.. (2002) p21-activated kinase increases the calcium sensitivity of rat triton-skinned cardiac muscle fiber bundles via a mechanism potentially involving novel phosphorylation of troponin I.. Circulation research, (20): [PMID:12242269]
12. Mogensen, Jens J and 8 more authors.. (2003) Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations.. The Journal of clinical investigation, [PMID:12531876]
13. Richard, Pascale P and 16 more authors.. (2003) Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy.. Circulation, (6): [PMID:12707239]
14. Erdmann, J J and 10 more authors.. (2003) Mutation spectrum in a large cohort of unrelated consecutive patients with hypertrophic cardiomyopathy.. Clinical genetics, [PMID:12974739]
15. Murphy, Ross T RT and 5 more authors.. (2004) Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy.. Lancet (London, England), (31): [PMID:15070570]
16. Haworth, Robert S RS and 6 more authors.. (2004) Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function.. Circulation research, (26): [PMID:15514163]
17. Kedar, Vishram V and 5 more authors.. (2004) Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.. Proceedings of the National Academy of Sciences of the United States of America, (28): [PMID:15601779]
18. Ingles, J J and 5 more authors.. (2005) Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling.. Journal of medical genetics, [PMID:16199542]
19. You, Bei B and 7 more authors.. (2009) Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1.. The Biochemical journal, (15): [PMID:18986304]
20. Carballo, Sebastian S and 9 more authors.. (2009) Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy.. Circulation research, (14): [PMID:19590045]
21. Millat, Gilles G and 13 more authors.. Clinical and mutational spectrum in a cohort of 105 unrelated patients with dilated cardiomyopathy.. European journal of medical genetics, [PMID:21846512]
22. Zhang, Pingbo P and 6 more authors.. (2012) Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart.. Circulation, (9): [PMID:22972900]

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体积（添加到小瓶中）

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Recombinant Troponin I/TNNI3 Antibody

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

图片

关联靶点（人）

安全和危险性（GHS）

质量标准

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

可替换产品

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

Recombinant Troponin I/TNNI3 Antibody

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

图片

关联靶点（人）

安全和危险性（GHS）

质量标准

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

可替换产品

参考文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器