| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A432034-10ml |
10ml |
现货  |
| |
| A432034-50ml |
50ml |
期货 |
|
| 英文别名 | Amfotericina B [INN-Spanish] | BRN 0078342 | EINECS 215-742-2 | MFCD00877763 | Amphotericin B liposome | C06573 | AMPH-B | AMPHOTERACIN B | AMPHOTERICIN B [JAN] | Mysteclin-F | Q412223 | s1636 | 1397-89-3, C47H73NO17 | Amphotericin B, Streptomyces nodosus |
|---|---|
| 规格或纯度 | BioReagent, 无菌过滤, 用于细胞培养, 无菌, 250 μg/mL |
| 稳定性与储存 | Store at 2-8℃ short term (1 month). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. |
| 英文名称 | Amphotericin B Solution |
| 生化机理 | 两性霉素B对真菌和酵母最有效。它通过结合与膜相关的固醇而形成跨膜通道，从而导致小分子的泄漏。尽管两性霉素B是治疗真菌病的有效抗生素，它会引起毒性。 两性霉素B是一种来自 链霉菌 的多烯抗真菌抗生素，临床上用于治疗系统性真菌感染。它对真菌和细菌细胞膜的固醇，尤其是麦角固醇具有很高的亲和力。 维持抗真菌细胞培养的正常用量为2.5 mg/L，同时在培养基中使用青霉素和链霉素。 |
| 储存温度 | 避光,-20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 备注 | 注意: 两性霉素B在37°C的培养条件下可保持活性3天。 |
| 产品介绍 |
两性霉素B是由结节链霉菌产生的多烯抗真菌抗生素。它可以与甾醇结合形成跨膜通道，导致细 胞内物质的泄漏，从而抑制真菌和酵母污染。两性霉素B抗真菌谱广，几乎对绝大部分真菌均有效，耐药菌株少见，高浓度时呈杀菌作用。两性霉素B溶液在室温不稳定，易被光、热和酸破坏。 |
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 有机氧化合物 |
| 类（Class) | 有机氧化合物 |
| 亚类（Subclass） | 碳水化合物和碳水化合物结合物 |
| 中间层级节点（Intermediate Tree Nodes） | 氨基糖 |
| 直接上位类(Direct Parent) | 氨基糖苷类 |
| 其他上位类（Alternative Parents） | 大环内酯类及其类似物 己糖 O-糖基化合物 β羟基酸及其衍生物 氧烷 二羧酸及其衍生物 仲醇 1,2-氨基醇 氨基酸 内酯 半缩醛 羧酸酯 多元醇 氧环化合物 缩醛 羧酸 羰基化合物 碳氢化合物衍生物 单烷基胺 有机氧化物 有机光子化合物 |
| 分子骨架（Molecular Framework) | Aliphatic heteropolycyclic compounds |
| 取代基（Substituents） | Aminoglycoside core - Macrolide - Hexose monosaccharide - O-glycosyl compound - Glycosyl compound - Beta-hydroxy acid - Dicarboxylic acid or derivatives - Oxane - Hydroxy acid - Monosaccharide - 1,2-aminoalcohol - Hemiacetal - Secondary alcohol - Lactone - Carboxylic acid ester - Amino acid or derivatives - Amino acid - Carboxylic acid derivative - Polyol - Organoheterocyclic compound - Oxacycle - Acetal - Carboxylic acid - Organic nitrogen compound - Primary aliphatic amine - Organonitrogen compound - Carbonyl group - Primary amine - Hydrocarbon derivative - Organic oxide - Amine - Alcohol - Organopnictogen compound - Aliphatic heteropolycyclic compound |
| 描述（Description） | 该化合物属于有机化合物类别中的氨基糖苷类。这类分子或分子片段由氨基修饰的糖类构成。 |
| 外部描述符（External Descriptors） | Polyenes |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 231-791-2 |
|---|---|
| 分子类型 | 生物试剂/缓冲液 |
| IIUPAC Name | (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid |
| INCHI | 1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1 |
| InChi Key | APKFDSVGJQXUKY-INPOYWNPSA-N |
| Smiles | CC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O |
| Isomeric SMILES | C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O |
| 分子量 | 924.08 |
| Beilstein号 | 78342 |
| Reaxy-Rn | 31131291 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31131291&ln= |
| 敏感性 | Light-sensitive |
|---|---|
| 熔点 | >170°C |
| 分子量 | 924.100 g/mol |
| XLogP3 | 0.000 |
| 氢键供体数Hydrogen Bond Donor Count | 12 |
| 氢键受体数Hydrogen Bond Acceptor Count | 18 |
| 可旋转键计数Rotatable Bond Count | 3 |
| 精确质量Exact Mass | 923.488 Da |
| 单同位素质量Monoisotopic Mass | 923.488 Da |
| 拓扑极表面积Topological Polar Surface Area | 320.000 Ų |
| 重原子数Heavy Atom Count | 65 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 1670.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 19 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 7 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 7 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | Warning |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P321: 特殊处理（请参阅此标签上的...）。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P403+P233: 存放在通风良好的地方。保持容器密闭。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| 个人防护装备 | Eyeshields,Gloves,half-mask respirator (EU),half-mask respirator (US),multi-purpose combination respirator cartridge (US) |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ25F0927373 |
分析证书 | 25-09-18 | A432034 |
| ZJ25F0927372 |
分析证书 | 25-09-18 | A432034 |
| ZJ25F0724400 |
分析证书 | 25-07-21 | A432034 |
| ZJ25F0724399 |
分析证书 | 25-07-21 | A432034 |
| 1. J Bolard,P Legrand,F Heitz,B Cybulska. (1991-06-11) One-sided action of amphotericin B on cholesterol-containing membranes is determined by its self-association in the medium.. Biochemistry, 30 ((23)): (5707-5715). [PMID:2043613] |
| 2. Ulisse Garbin,Anna Fratta Pasini,Chiara Stranieri,Stefania Manfro,Chiara Mozzini,Veronica Boccioletti,Andrea Pasini,Mattia Cominacini,Stefano Evangelista,Luciano Cominacini. (2008-04-26) Effects of nebivolol on endothelial gene expression during oxidative stress in human umbilical vein endothelial cells.. Mediators of inflammation, 2008 (367590-367590). [PMID:18437228] |
| 3. Boris Musset,Deri Morgan,Vladimir V Cherny,Donald W MacGlashan,Larry L Thomas,Eduardo Ríos,Thomas E DeCoursey. (2008-07-31) A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils.. Proceedings of the National Academy of Sciences of the United States of America, 105 ((31)): (11020-11025). [PMID:18664579] |
| 4. Elodie Fino,Jean-Michel Deniau,Laurent Venance. (2009-08-14) Brief subthreshold events can act as Hebbian signals for long-term plasticity.. PloS one, 4 ((8)): (e6557-e6557). [PMID:19675683] |
| 5. Antonio M Galvao,David W Ramilo,Dariusz J Skarzynski,Karolina Lukasik,Angela Tramontano,Antonio Mollo,Luisa M Mateus,Graca Maria L Ferreira-Dias. (2010-08-20) Is FAS/Fas ligand system involved in equine corpus luteum functional regression?. Biology of reproduction, 83 ((6)): (901-908). [PMID:20720169] |
| 6. Michael Klepser. (2010-10-19) The value of amphotericin B in the treatment of invasive fungal infections.. Journal of critical care, 26 ((2)): (225-225). [PMID:20951541] |
| 7. Matteo Bassetti,Franco Aversa,Filippo Ballerini,Fabio Benedetti,Alessandro Busca,Nicola Cascavilla,Ercole Concia,Andrea Tendas,Francesco Di Raimondo,Patrizio Mazza,Anna Maria Nosari,Giuseppe Rossi. (2011-09-06) Amphotericin B lipid complex in the management of invasive fungal infections in immunocompromised patients.. Clinical drug investigation, 31 ((11)): (745-758). [PMID:21888451] |
| 8. Rive Sarfstein,Ilan Bruchim,Ami Fishman,Haim Werner. (2011-09-21) The mechanism of action of the histone deacetylase inhibitor vorinostat involves interaction with the insulin-like growth factor signaling pathway.. PloS one, 6 ((9)): (e24468-e24468). [PMID:21931726] |
| 9. Luigina Romani. (2012-09-05) Amphotericin B still in the headlines.. Pathogens and global health, 106 ((2)): (80-81). [PMID:22943542] |
| 10. Iman Karimzadeh,Shadi Farsaei,Hossein Khalili,Simin Dashti-Khavidaki. (2012-09-07) Are salt loading and prolonging infusion period effective in prevention of amphotericin B-induced nephrotoxicity?. Expert opinion on drug safety, 11 ((6)): (969-983). [PMID:22950480] |
| 11. Manica Balasegaram,Koert Ritmeijer,Maria Angeles Lima,Sakib Burza,Gemma Ortiz Genovese,Barbara Milani,Sara Gaspani,Julien Potet,François Chappuis. (2012-11-22) Liposomal amphotericin B as a treatment for human leishmaniasis.. Expert opinion on emerging drugs, 17 ((4)): (493-510). [PMID:23167833] |
| 12. Iman Karimzadeh,Hossein Khalili,Shadi Farsaei,Simin Dashti-Khavidaki,Mohammad Mahdi Sagheb. (2013-01-31) Role of diuretics and lipid formulations in the prevention of amphotericin B-induced nephrotoxicity.. European journal of clinical pharmacology, 69 ((7)): (1351-1368). [PMID:23361383] |
| 13. John E Linley. (2013-03-27) Perforated whole-cell patch-clamp recording.. Methods in molecular biology (Clifton, N.J.), 998 (149-157). [PMID:23529427] |
| 14. Mariusz Dyląg,Paweł Lis,Katarzyna Niedźwiecka,Young H Ko,Peter L Pedersen,Andre Goffeau,Stanisław Ułaszewski. (2013-04-02) 3-Bromopyruvate: a novel antifungal agent against the human pathogen Cryptococcus neoformans.. Biochemical and biophysical research communications, 434 ((2)): (322-327). [PMID:23541578] |
| 15. Jeremy N Day,Tran T H Chau,Marcel Wolbers,Pham P Mai,Nguyen T Dung,Nguyen H Mai,Nguyen H Phu,Ho D Nghia,Nguyen D Phong,Cao Q Thai,Le H Thai,Ly V Chuong,Dinh X Sinh,Van A Duong,Thu N Hoang,Pham T Diep,James I Campbell,Tran P M Sieu,Stephen G Baker,Nguyen V V Chau,Tran T Hien,David G Lalloo,Jeremy J Farrar. (2013-04-05) Combination antifungal therapy for cryptococcal meningitis.. The New England journal of medicine, 368 ((14)): (1291-1302). [PMID:23550668] |
| 16. (2013-04-12) Treating cryptococcal meningitis in people with HIV.. BMJ (Clinical research ed.), 346 (f2203-f2203). [PMID:23575571] |
| 17. Surjit Lidder,A Tasleem,S Masterson,R W J Carrington. (2013-05-31) Candida tropicalis: diagnostic dilemmas for an unusual prosthetic hip infection.. Journal of the Royal Army Medical Corps, 159 ((2)): (123-125). [PMID:23720596] |
| 18. Richard J Hamill. (2013-06-04) Amphotericin B formulations: a comparative review of efficacy and toxicity.. Drugs, 73 ((9)): (919-934). [PMID:23729001] |
| 19. Masaki Fujita,Jun Yanagisawa,Masafumi Hiratsuka,Takeshi Shiraishi,Ryosuke Hirano,Takemasa Matsumoto,Motokimi Shiraishi,Akinori Iwasaki,Kentaro Watanabe. (2013-06-20) [A case report of pulmonary aspergillosis in lung transplant recipient successfully treated with inhalation administration of liposomal amphotericin B].. The Japanese journal of antibiotics, 66 ((1)): (37-43). [PMID:23777015] |
| 20. Patrícia L N Néris,John P A Caldas,Yara K S Rodrigues,Francianne M Amorim,Jacqueline A Leite,Sandra Rodrigues-Mascarenhas,José M Barbosa-Filho,Luis C Rodrigues,Márcia R Oliveira. (2013-07-31) Neolignan Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro.. Experimental parasitology, 135 ((2)): (307-313). [PMID:23891943] |
| 21. Pirouz M Daftarian,Geoffrey W Stone,Leticia Kovalski,Manoj Kumar,Aram Vosoughi,Maitee Urbieta,Pat Blackwelder,Emre Dikici,Paolo Serafini,Stephanie Duffort,Richard Boodoo,Alhelí Rodríguez-Cortés,Vance Lemmon,Sapna Deo,Jordi Alberola,Victor L Perez,Sylvia Daunert,Arba L Ager. (2013-08-01) A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis.. The Journal of infectious diseases, 208 ((11)): (1914-1922). [PMID:23901083] |
| 22. D Standaert,F Laurent,S Jonckheere,J M Scheiff,B Vandercam,J C Yombi. (2013-08-24) Relapsing visceral leishmaniasis in a HIV-1 infected patient with advanced disease.. Acta clinica Belgica, 68 ((2)): (124-127). [PMID:23967722] |
| 23. Katrina A Brandis,Sarah Gale,Sarah Jinn,Stephen J Langmade,Nicole Dudley-Rucker,Hui Jiang,Rohini Sidhu,Aileen Ren,Anna Goldberg,Jean E Schaffer,Daniel S Ory. (2013-11-01) Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular cholesterol trafficking.. The Journal of biological chemistry, 288 ((50)): (35703-35713). [PMID:24174535] |
| 24. Noelle Layer,Vicky Cevallos,Andrew J Maxwell,Caroline Hoover,Jeremy D Keenan,Bennie H Jeng. (2014-05-03) Efficacy and safety of antifungal additives in Optisol-GS corneal storage medium.. JAMA ophthalmology, 132 ((7)): (832-837). [PMID:24789459] |
| 25. Chitralekha Mohanty,Katarzyna Zielinska-Chomej,Margareta Edgren,Ryoichi Hirayama,Takeshi Murakami,Bengt Lind,Iuliana Toma-Dasu. (2014-06-13) Predicting the sensitivity to ion therapy based on the response to photon irradiation--experimental evidence and mathematical modelling.. Anticancer research, 34 ((6)): (2801-2806). [PMID:24922642] |
| 26. R Bini,A Addeo,L Maganuco,D Fontana,T Viora,R Leli. (2014-07-06) The role of surgery in a case of diffuse mucormycosis with haematemesis and gastric necrosis.. Annals of the Royal College of Surgeons of England, 96 ((5)): (e31-e33). [PMID:24992411] |
| 27. Andrew M Morris. (2014-07-16) Review: voriconazole for prevention or treatment of invasive fungal infections in cancer with neutropenia.. Annals of internal medicine, 161 ((2)): (JC8-JC8). [PMID:25023274] |
| 28. Maria Teresa Montagna,Grazia Lovero,Caterina Coretti,Osvalda De Giglio,Domenico Martinelli,Andrea Bedini,Mario Delia,Antonio Rosato,Mauro Codeluppi,Giuseppina Caggiano. (2014-09-12) In vitro activities of amphotericin B deoxycholate and liposomal amphotericin B against 604 clinical yeast isolates.. Journal of medical microbiology, 63 ((Pt 12)): (1638-1643). [PMID:25210203] |
| 29. Ermias Diro,Lutgarde Lynen,Berhane Gebregziabiher,Abraham Assefa,Wubishet Lakew,Zewdu Belew,Asrat Hailu,Marleen Boelaert,Johan van Griensven. (2014-10-21) Clinical aspects of paediatric visceral leishmaniasis in North-west Ethiopia.. Tropical medicine & international health : TM & IH, 20 ((1)): (8-16). [PMID:25329449] |
| 30. Alyse N Douglass,Heather S Kain,Marian Abdullahi,Nadia Arang,Laura S Austin,Sebastian A Mikolajczak,Zachary P Billman,Jen C C Hume,Sean C Murphy,Stefan H I Kappe,Alexis Kaushansky. (2015-02-05) Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.. Molecular therapy : the journal of the American Society of Gene Therapy, 23 ((5)): (857-865). [PMID:25648263] |
| 31. Haruka Takahashi,Hiroshi Ishikawa,Izumi Mataga,Akira Tanaka. (2015-02-26) Establishment and characterization of human lingual squamous cell carcinoma cell lines designated Nialym derived from metastatic foci of lymph node, and Nialymx derived from transplanted tumor of Nialym cells.. Human cell, 28 ((3)): (143-153). [PMID:25711304] |
| 32. Richard C Condit,Nissin Moussatche. (2015-04-13) The vaccinia virus E6 protein influences virion protein localization during virus assembly.. Virology, 482 (147-156). [PMID:25863879] |
| 33. E Martínez-León,C Osycka-Salut,J Signorelli,P Pozo,B Pérez,M Kong,P Morales,S Pérez-Martínez,E S Díaz. (2015-06-26) Fibronectin stimulates human sperm capacitation through the cyclic AMP/protein kinase A pathway.. Human reproduction (Oxford, England), 30 ((9)): (2138-2151). [PMID:26109618] |
| 34. Amparo Estepa,Julio Coll. (2015-09-13) Inhibition of SERPINe1 reduces rhabdoviral infections in zebrafish.. Fish & shellfish immunology, 47 ((1)): (264-270). [PMID:26363229] |
| 35. Kohei Okuyama,Keiji Suzuki,Souichi Yanamoto,Tomofumi Naruse,Hiroki Tsuchihashi,Shunichi Yamashita,Masahiro Umeda. (2018-08-08) Anaplastic transition within the cancer microenvironment in early-stage oral tongue squamous cell carcinoma is associated with local recurrence.. International journal of oncology, 53 ((4)): (1713-1720). [PMID:30085337] |
| 36. Deniz Gulfem Ozturk,Muhammed Kocak,Arzu Akcay,Kubilay Kinoglu,Erdogan Kara,Yalcin Buyuk,Hilal Kazan,Devrim Gozuacik. (2018-10-07) MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress.. Autophagy, 15 ((3)): (375-390). [PMID:30290719] |
| 37. Kristopher R Genschmer,Derek W Russell,Charitharth Lal,Tomasz Szul,Preston E Bratcher,Brett D Noerager,Mojtaba Abdul Roda,Xin Xu,Gabriel Rezonzew,Liliana Viera,Brian S Dobosh,Camilla Margaroli,Tarek H Abdalla,Robert W King,Carmel M McNicholas,J Michael Wells,Mark T Dransfield,Rabindra Tirouvanziam,Amit Gaggar,J Edwin Blalock. (2019-01-12) Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.. Cell, 176 ((1-2)): (113-126). [PMID:30633902] |
| 38. Rebecca M Wadey,Katherine D Connolly,Donna Mathew,Gareth Walters,D Aled Rees,Philip E James. (2019-02-17) Inflammatory adipocyte-derived extracellular vesicles promote leukocyte attachment to vascular endothelial cells.. Atherosclerosis, 283 (19-27). [PMID:30771557] |
| 39. Saira Tabassum,Muhammad Zia,Esperanza J Carcahe de Blanco,Riffat Batool,Roohi Aslam,Sajid Hussain,Qamar Wali,Muhammad Mudassar Gulzar. (2019-09-16) Phytochemical, in-vitro biological and chemo-preventive profiling of Arisaema jacquemontii Blume tuber extracts.. BMC complementary and alternative medicine, 19 ((1)): (256-256). [PMID:31521162] |
| 40. Hee Chan Yoo,Seung Joon Park,Miso Nam,Juwon Kang,Kibum Kim,Joo Hye Yeo,Joon-Ki Kim,Yunkyung Heo,Hee Seung Lee,Myeong Youl Lee,Chang Woo Lee,Jong Soon Kang,Yun-Hee Kim,Jinu Lee,Junjeong Choi,Geum-Sook Hwang,Seungmin Bang,Jung Min Han. (2019-12-24) A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells.. Cell metabolism, 31 ((2)): (267-283). [PMID:31866442] |
| 41. Ana Amaral,Carina Fernandes,Maria Rosa Rebordão,Anna Szóstek-Mioduchowska,Karolina Lukasik,Barbara Gawronska-Kozak,Luís Telo da Gama,Dariusz J Skarzynski,Graça Ferreira-Dias. (2020-05-21) The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium.. Animals : an open access journal from MDPI, 10 ((5)): [PMID:32429399] |
| 42. Joanne Marie M Del Rosario,Matthew Smith,Kam Zaki,Paul Risley,Nigel Temperton,Othmar G Engelhardt,Mary Collins,Yasuhiro Takeuchi,Simon E Hufton. (2020-06-18) Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity.. Frontiers in immunology, 11 (627-627). [PMID:32547534] |
| 43. Steven D Forsythe,Shyama Sasikumar,Omeed Moaven,Hemamylammal Sivakumar,Perry Shen,Edward A Levine,Shay Soker,Aleksander Skardal,Konstantinos I Votanopoulos. (2020-07-08) Personalized Identification of Optimal HIPEC Perfusion Protocol in Patient-Derived Tumor Organoid Platform.. Annals of surgical oncology, 27 ((13)): (4950-4960). [PMID:32632882] |
| 44. Bastian Niklas Hölzel,Kurt Pfannkuche,Bernhard Allner,Hans Thomas Allner,Jürgen Hescheler,Daniel Derichsweiler,Henner Hollert,Andreas Schiwy,Julia Brendt,Michael Schaffeld,Alexander Froschauer,Petra Stahlschmidt-Allner. (2020-07-24) Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells.. Archives of toxicology, 94 ((9)): (3265-3280). [PMID:32700163] |
| 45. Guo-Kai Wang,Jai-Sing Yang,Yu-Fei Huang,Jin-Song Liu,Chia-Wen Tsai,DA-Tian Bau,Wen-Shin Chang. (2021-01-07) Culture Separation, Identification and Unique Anti-pathogenic Fungi Capacity of Endophytic Fungi from Gucheng Salvia Miltiorrhiza.. In vivo (Athens, Greece), 35 ((1)): (325-332). [PMID:33402481] |
| 46. Reem El-Gendy,Sarah Junaid,Stephen K L Lam,Karen M Elson,Joanne L Tipper,Richard M Hall,Eileen Ingham,Jennifer Kirkham. (2021-02-05) Developing a Tooth in situ Organ Culture Model for Dental and Periodontal Regeneration Research.. Frontiers in bioengineering and biotechnology, 8 (581413-581413). [PMID:33537288] |
| 47. Kielan Darcy McAlinden,Wenying Lu,Parisa Vahidi Ferdowsi,Stephen Myers,James Markos,Josie Larby,Collin Chia,Heinrich C Weber,Greg Haug,Mathew Suji Eapen,Sukhwinder Singh Sohal. (2021-04-04) Electronic Cigarette Aerosol Is Cytotoxic and Increases ACE2 Expression on Human Airway Epithelial Cells: Implications for SARS-CoV-2 (COVID-19).. Journal of clinical medicine, 10 ((5)): [PMID:33802256] |
| 48. Alexandra M S Soares,Luciana M R Alencar,Lucas P Dias,Ruana C Lima,Carolina Rocha Silva,Ralph Santos-Oliveira,Jose T A Oliveira,Livio M C Junior,Pedro F N Souza. (2021-07-25) New Insights into Anthelmintic Mechanisms of Action of a Synthetic Peptide: An Ultrastructural and Nanomechanical Approach.. Polymers, 13 ((14)): [PMID:34301127] |
| 49. Lukasz Czekala,Roman Wieczorek,Liam Simms,Fan Yu,Jessica Budde,Edgar Trelles Sticken,Kathryn Rudd,Thomas Verron,Oleg Brinster,Matthew Stevenson,Tanvir Walele. (2021-08-05) Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke.. Current research in toxicology, 2 (99-115). [PMID:34345855] |
| 50. Yumiko Hirokawa,Jordan Clarke,Michelle Palmieri,Tao Tan,Dmitri Mouradov,Shan Li,Cong Lin,Fuqiang Li,Huijuan Luo,Kui Wu,Maree Faux,Chin Wee Tan,Margaret Lee,Grace Gard,Peter Gibbs,Antony W Burgess,Oliver M Sieber. (2021-09-15) Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine.. Communications biology, 4 ((1)): (1067-1067). [PMID:34518628] |
| 51. Anine Crous,Heidi Abrahamse. (2021-09-17) Aluminium (III) phthalocyanine chloride tetrasulphonate is an effective photosensitizer for the eradication of lung cancer stem cells.. Royal Society open science, 8 ((9)): (210148-210148). [PMID:34527268] |
| 52. Siv Anita Hegre,Helle Samdal,Antonin Klima,Endre B Stovner,Kristin G Nørsett,Nina Beate Liabakk,Lene Christin Olsen,Konika Chawla,Per Arne Aas,Pål Sætrom. (2021-09-25) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation.. Scientific reports, 11 ((1)): (18952-18952). [PMID:34556693] |
| 53. Hanieh Montaseri,Cherie Ann Kruger,Heidi Abrahamse. (2021-09-29) Targeted Photodynamic Therapy Using Alloyed Nanoparticle-Conjugated 5-Aminolevulinic Acid for Breast Cancer.. Pharmaceutics, 13 ((9)): [PMID:34575450] |
| 54. Sze Wan Hung,Bo Liang,Yating Gao,Ruizhe Zhang,Zhouyurong Tan,Tao Zhang,Pui Wah Jacqueline Chung,Tak Hang Chan,Chi Chiu Wang. (2021-11-02) An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis.. Frontiers in pharmacology, 12 (714790-714790). [PMID:34721014] |
| 55. R Scott Pearsall,Ernesto Canalis,Milton Cornwall-Brady,Kathryn W Underwood,Brendan Haigis,Jeffrey Ucran,Ravindra Kumar,Eileen Pobre,Asya Grinberg,Eric D Werner,Vaida Glatt,Lisa Stadmeyer,Deanna Smith,Jasbir Seehra,Mary L Bouxsein. (2008-05-08) A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.. Proceedings of the National Academy of Sciences of the United States of America, 105 ((19)): (7082-7087). [PMID:18460605] |
| 56. João F Lacerda,Carlos Meneses Oliveira. (2013-02-13) Diagnosis and treatment of invasive fungal infections focus on liposomal amphotericin B.. Clinical drug investigation, 33 Suppl 1 (S5-14). [PMID:23381977] |
| 57. Angela S Loo,Saif A Muhsin,Thomas J Walsh. (2013-08-13) Toxicokinetic and mechanistic basis for the safety and tolerability of liposomal amphotericin B.. Expert opinion on drug safety, 12 ((6)): (881-895). [PMID:23931455] |
| 58. Konstantin A Krychtiuk,Lukas Watzke,Christoph Kaun,Elisabeth Buchberger,Renate Hofer-Warbinek,Svitlana Demyanets,Julia Pisoni,Stefan P Kastl,Sabine Rauscher,Marion Gröger,Arezu Aliabadi,Andreas Zuckermann,Gerald Maurer,Rainer de Martin,Kurt Huber,Johann Wojta,Walter S Speidl. (2014-10-03) Levosimendan exerts anti-inflammatory effects on cardiac myocytes and endothelial cells in vitro.. Thrombosis and haemostasis, 113 ((2)): (350-362). [PMID:25273157] |
| 59. Stefanie Schrauwen,Lieve Coenegrachts,Anna Cattaneo,Els Hermans,Diether Lambrechts,Frédéric Amant. (2015-06-09) The antitumor effect of metformin with and without carboplatin on primary endometrioid endometrial carcinoma in vivo.. Gynecologic oncology, 138 ((2)): (378-382). [PMID:26050920] |
| 60. Maddalena Nano,Simon Gemble,Anthony Simon,Carole Pennetier,Vincent Fraisier,Veronique Marthiens,Renata Basto. (2019-11-12) Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells.. Current biology : CB, 29 ((22)): (3937-3945). [PMID:31708395] |
| 61. Kausar Sadia Fakhruddin,Hiroshi Egusa,Hien Chi Ngo,Chamila Panduwawala,Siripen Pesee,Thenmozhi Venkatachalam,Lakshman Perera Samaranayake. (2020-04-17) Silver diamine fluoride (SDF) used in childhood caries management has potent antifungal activity against oral Candida species.. BMC microbiology, 20 ((1)): (95-95). [PMID:32295517] |
| 62. Ana Amaral,Carina Fernandes,Sofia Morazzo,Maria Rosa Rebordão,Anna Szóstek-Mioduchowska,Karolina Lukasik,Barbara Gawronska-Kozak,Luís Telo da Gama,Dariusz Jan Skarzynski,Graça Ferreira-Dias. (2020-11-17) The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare.. Frontiers in veterinary science, 7 (582211-582211). [PMID:33195599] |
| 63. Greta Klejborowska,Alicja Urbaniak,Ewa Maj,Joanna Wietrzyk,Mahshad Moshari,Jordane Preto,Jack A Tuszynski,Timothy C Chambers,Adam Huczyński. (2021-01-20) Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives.. Bioorganic & medicinal chemistry, 32 (116014-116014). [PMID:33465696] |
| 64. Safa Oufensou,Stefano Casalini,Virgilio Balmas,Paola Carta,Wiem Chtioui,Maria A Dettori,Davide Fabbri,Quirico Migheli,Giovanna Delogu. (2021-01-31) Prenylated Trans-Cinnamic Esters and Ethers against Clinical Fusarium spp.: Repositioning of Natural Compounds in Antimicrobial Discovery.. Molecules (Basel, Switzerland), 26 ((3)): [PMID:33513915] |
| 65. Yu Hu,Yun Zhu,Skyler D Gerber,Jared M Osland,Min Chen,Krishna A Rao,Heng Gu,Rong Yuan. (2021-03-12) Deletion of Nrip1 delays skin aging by reducing adipose-derived mesenchymal stem cells (ADMSCs) senescence, and maintaining ADMSCs quiescence.. GeroScience, 43 ((4)): (1815-1833). [PMID:33704619] |
| 66. Yu-Ting Kuo,Ching-Hsuan Liu,Angela Corona,Elisa Fanunza,Enzo Tramontano,Liang-Tzung Lin. (2021-09-29) The Methanolic Extract of Perilla frutescens Robustly Restricts Ebola Virus Glycoprotein-Mediated Entry.. Viruses, 13 ((9)): [PMID:34578374] |
| 67. Ana Amaral,Carina Fernandes,Anna Szóstek-Mioduchowska,Karolina Lukasik,Maria Rosa Rebordão,Pedro Pinto-Bravo,Dariusz Jan Skarzynski,Graça Ferreira-Dias. (2021-10-24) The Inhibitory Effect of Noscapine on the In Vitro Cathepsin G-Induced Collagen Expression in Equine Endometrium.. Life (Basel, Switzerland), 11 ((10)): [PMID:34685478] |
首页
400-620-6333
