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3′-叠氮-3′-脱氧胸苷, 人体免疫缺陷病毒 1 型逆转录酶抑制剂

核苷逆转录酶抑制剂（NRTI）
35篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
A122924-1g
 1g 现货 Stock Image
A122924-5g
 5g 现货 Stock Image
A122924-25g
 25g 现货 Stock Image
A122924-100g
 100g 现货 Stock Image
大包装询价 收藏夹 比较  SDS中文版  DATASHEET
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Anti-infection (2825) Cell Cycle/DNA Damage (2603) CRISPR/Cas9 (10) HIV (248) 六元杂环化合物 (1702) 嘧啶类 (541)
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基本描述

别名 齐多夫定 | 叠氮胸苷 | 1-(3-叠氮基-2,3-二脱氧-β-D-呋喃核糖基)胸腺嘧啶
英文别名 3'-Azido-2',3'-Dideoxythymidine | 4B9XT59T7S | DTXSID8020127 | Racemic Liposomal AZT | Aziodothymidine | HSDB 6515 | Met-SDF-1.beta. & Zidovudine | AZT | AZT & PM-19 | NSC-602670 | Zidovudinum [Latin] | zudovidine | zidovudin | 3'-Azido-3'-deoxythymidine
规格或纯度 Moligand™, ≥98%(HPLC)
英文名称 3′-Azido-3′-deoxythymidine
生化机理 齐多夫定（Azidothymidine，AZT）是一种核苷类似物逆转录酶抑制剂（NRTI），是一种用于治疗艾滋病毒/艾滋病感染的抗逆转录病毒药物。抗逆转录病毒药物，可透过血脑屏障。
应用 An inhibitor of HIV-1 reverse transcriptase.
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
作用类型 抑制剂
作用机制 人体免疫缺陷病毒 1 型逆转录酶抑制剂
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

对 HIV-1 病毒有效的逆转录酶抑制剂An inhibitor of HIV-1 reverse transcriptase.

3′-Azido-3′-deoxythymidine is an inhibitor of HIV-1 RT (HIV-1 reverse transcriptase) that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.
An inhibitor of HIV-1 reverse transcriptase.

关联靶点（人）

PDE5A Tclin Phosphodiesterase 5A (5113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
F2 Tclin Thrombin (11687 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
INSR Tclin Insulin receptor (5558 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CRHR1 Tclin Corticotropin releasing factor receptor 1 (2996 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GCGR Tclin Glucagon receptor (2563 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

pol Human immunodeficiency virus type 1 protease (9113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TK Thymidine kinase (276 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
pol Human immunodeficiency virus type 1 reverse transcriptase (18245 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
tmk Thymidylate kinase (360 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Sigmar1 Sigma opioid receptor (160 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cckar Cholecystokinin A receptor (90 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ntsr1 Neurotensin receptor 1 (48 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pde4d Phosphodiesterase 4D (4 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bdkrb1 Bradykinin B1 receptor (77 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
dnk Deoxynucleoside kinase (95 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
deoA Thymidine phosphorylase (531 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Abcc1 Multidrug resistance-associated protein 1 (42 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Prkcb Protein kinase C beta (2 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hcar2 Hydroxycarboxylic acid receptor 2 (55 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus sp. (212 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus pyogenes (16140 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mycobacterium intracellulare (1532 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Leishmania donovani (89745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Trypanosoma cruzi (99888 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human alphaherpesvirus 2 (4932 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human betaherpesvirus 5 (5122 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human alphaherpesvirus 1 (11089 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hepatitis B virus (7925 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human immunodeficiency virus 1 (70413 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Simian immunodeficiency virus (338 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Moloney murine leukemia virus (54 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Moloney murine sarcoma virus (182 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Avian myeloblastosis virus (26 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human T-cell leukemia virus type I (114 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rotavirus (147 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
West Nile virus (623 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

分子类型 小分子
IUPAC Name 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
INCHI InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChi Key HBOMLICNUCNMMY-XLPZGREQSA-N
Canonical SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
Isomeric SMILES CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-]
WGK Germany 3
RTECS XP2072000
PubChem CID 35370
分子量 267.24
Beilstein号 3595791
Reaxy-Rn 3595791

化学和物理性质

溶解性 Soluble in water (50 mg/ml), DMSO, and methanol.
敏感性 对光敏感，易吸潮
比旋光度 47° (C=1,H2O)
熔点 124 °C
分子量 267.240 g/mol
XLogP3 0.000
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 6
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 267.097 Da
单同位素质量Monoisotopic Mass 267.097 Da
拓扑极表面积Topological Polar Surface Area 93.200 Ų
重原子数Heavy Atom Count 19
形式电荷Formal Charge 0
复杂度Complexity 484.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 3
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS08
信号词 Danger
危险声明

H341: 怀疑引起遗传缺陷

H351: 怀疑引起遗传缺陷

H372: 通过长时间或反复暴露对器官造成损害

H350: 可能导致癌症

H361: 怀疑破坏生育力或未出生的孩子
预防措施声明

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。

P281: 根据需要使用个人防护设备。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P203: 使用前，获取、阅读并遵守所有安全说明。

P318: 如果暴露或担心，请就医。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
RTECS XP2072000
Reaxy-Rn 3595791
Merck Index 10123
个人防护装备 Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

 SDS英文版

质量标准

Specific Rotation [a]20/D(c=1 in H2O) 43-51（°）
Melting point 122-126（℃）
Purity(HPLC) 99-100（%）
Appearance（A122924) White to Light Yellow Powder or Crystals
Infrared spectrum Conforms to Structure
Solubility,Colorless to faint yellow,clear(50 mg/mL, H2O) pass

 质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到10个结果

批号(Lot Number) 证书类型 日期 货号
C2504373 分析证书 24-07-12 A122924
C2504374 分析证书 24-07-12 A122924
C2504375 分析证书 24-07-12 A122924
L2306206 分析证书 23-12-11 A122924
E2231247 分析证书 22-03-15 A122924
E2231253 分析证书 22-03-15 A122924
E2231256 分析证书 22-03-15 A122924
E2231476 分析证书 22-03-15 A122924
C1826134 分析证书 22-01-19 A122924
C1826133 分析证书 22-01-19 A122924

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3. Long Ma, Wenlu Zhang, Lijuan Yin, Yaru Li, Jianwen Zhuang, Liang Shen, Shuli Man.  (2023)  A SERS-signalled, CRISPR/Cas-powered bioassay for amplification-free and anti-interference detection of SARS-CoV-2 in foods and environmental samples using a single tube-in-tube vessel.  JOURNAL OF HAZARDOUS MATERIALS,  452  (131195).  [PMID:36963196] [10.1016/j.jhazmat.2023.131195]
4. Shuai Liu, Keming Zheng, Yilin Jiang, Susu Gai, Bohan Li, Dehai Li, Shuang Yang, Zhihua Lv.  (2023)  Biotransformation of Penindolone, an Influenza A Virus Inhibitor.  MOLECULES,  28  (3): (1479).  [PMID:36771146] [10.3390/molecules28031479]
5. Bowen Huang, Jianjun Cui, Xinyi Chen, Yongjian Huang, Cong Xu, Enyi Xie.  (2022)  Mechanism of the allelopathic effect of macroalgae Gracilaria bailiniae on Nitzschia closterium.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,  241  (113767).  [PMID:35714486] [10.1016/j.ecoenv.2022.113767]
6. Zhihua Song, Jinqiu Liu, Deyang Zhang, Yumeng Wang, Wen Lin, Yi Bi, Hongbo Wang, Maryam Arabi, Jinhua Li, Jiping Ma, Yan Wang, Lingxin Chen.  (2022)  Synthesis of C8F13-SiO2 stationary phase for chromatographic separation of highly polar compounds.  MICROCHEMICAL JOURNAL,  181  (107670).  [10.1016/j.microc.2022.107670]
7. Xu Gui-Qing, Gong Xiao-Qing, Zhu Ying-Ying, Yao Xiao-Jun, Peng Li-Zeng, Sun Ge, Yang Jian-Xue, Mao Long-Fei.  (2022)  Novel 1,2,3-Triazole Erlotinib Derivatives as Potent IDO1 Inhibitors: Design, Drug-Target Interactions Prediction, Synthesis, Biological Evaluation, Molecular Docking and ADME Properties Studies.  Frontiers in Pharmacology,  13  [PMID:35677437] [10.3389/fphar.2022.854965]
8. Bo-Yang Li, Fei Yang, Zhong-Yu Zhang, Yu-Feng Shen, Tao Wang, Liang Zhao, Jia-Cheng Qin, Fei Ling, Gao-Xue Wang.  (2022)  Quinoline, with the active site of 8-hydroxyl, efficiently inhibits Micropterus salmoides rhabdovirus (MSRV) infection in vitro and in vivo.  JOURNAL OF FISH DISEASES,  45  (6): (895-905).  [PMID:35445749] [10.1111/jfd.13615]
9. Yongxing Zhang, Jia Hu, Yong Xu, Xiangyu Yan, Siqi Zhang, Kang Duan, Cheng Chen, Ye Yuan, Francis Verpoort.  (2022)  CO2-induced dissolution of ZnO into ionic liquids and its catalytic application for the hydration of propargylic alcohols.  APPLIED CATALYSIS B-ENVIRONMENTAL,  310  (121270).  [10.1016/j.apcatb.2022.121270]
10. Zhou Xinghong, Liu Xiaoyu, He Qiuxing, Wang Ming, Lu Hanqi, You Yanting, Chen Liqian, Cheng Jingru, Li Fei, Fu Xiuqiong, Kwan Hiu Yee, Zhou Lin, Zhao Xiaoshan.  (2022)  Ginger Extract Decreases Susceptibility to Dextran Sulfate Sodium-Induced Colitis in Mice Following Early Antibiotic Exposure.  Frontiers in Medicine,  8  [PMID:35071260] [10.3389/fmed.2021.755969]
11. Zhihua Song, Yanqin Song, Yinghao Wang, Jinqiu Liu, Yumeng Wang, Wen Lin, Yaqi Wang, Jinhua Li, Jiping Ma, Gangqiang Yang, Lingxin Chen.  (2022)  Chromatographic performance of zidovudine imprinted polymers coated silica stationary phases.  TALANTA,  239  (123115).  [PMID:34890940] [10.1016/j.talanta.2021.123115]
12. Lu Hanqi, You Yanting, Zhou Xinghong, He Qiuxing, Wang Ming, Chen Liqian, Zhou Lin, Sun Xiaomin, Liu Yanyan, Jiang Pingping, Dai Jiaojiao, Fu Xiuqiong, Kwan Hiu Yee, Zhao Xiaoshan, Lou Linjie.  (2021)  Citrus reticulatae pericarpium Extract Decreases the Susceptibility to HFD-Induced Glycolipid Metabolism Disorder in Mice Exposed to Azithromycin in Early Life.  Frontiers in Immunology,  12  [PMID:34868039] [10.3389/fimmu.2021.774433]
13. Muning Chen, Jian Lu, Jia Gao, Chao Yu, Wendong Xing, Jiangdong Dai, Minjia Meng, Yongsheng Yan, Yilin Wu.  (2022)  Design of self-cleaning molecularly imprinted membrane with antibacterial ability for high-selectively separation of ribavirin.  JOURNAL OF MEMBRANE SCIENCE,  642  (119994).  [10.1016/j.memsci.2021.119994]
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15. Zifei Qin, Peile Wang, Shuyi Duan, Xiaoying Wan, Han Xing, Jing Yang, Xiaojian Zhang, Zhihong Yao, Xinsheng Yao.  (2021)  Potential Determinants for Metabolic Fates and Inhibitory Effects of Isobavachalcone Involving in Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Efflux Transporters.  JOURNAL OF PHARMACEUTICAL SCIENCES,  110  (2285).  [PMID:33610566] [10.1016/j.xphs.2021.02.013]
16. Huixian Jia, Ningzhao Shang, Xiaobo He, Anaclet Nsabimana, Danna Sun, Huan Wang, Yufan Zhang.  (2021)  Epoxy-functionalized macroporous carbon with embedded platinum nanoparticles for electrochemical detection of telomerase activity via telomerase-triggered catalytic hairpin assembly.  TALANTA,  225  (121957).  [PMID:33592712] [10.1016/j.talanta.2020.121957]
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22. Xiang-Nan He, Ya-Ning Wang, Yue Wang, Zhang-Run Xu.  (2020)  Accurate quantitative detection of cell surface sialic acids with a background-free SERS probe.  TALANTA,  209  (120579).  [PMID:31892066] [10.1016/j.talanta.2019.120579]
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24. Fanyu Meng, Hua Chai, Xiaoyi Ma, Yuguo Tang, Peng Miao.  (2019)  FRET investigation toward DNA tetrahedron-based ratiometric analysis of intracellular telomerase activity.  Journal of Materials Chemistry B,  7  (11): (1926-1932).  [PMID:32255055] [10.1039/C9TB00001A]
25. Weijie Ding, Shengshi Xu, Xiaochun Yu, Shun Wang.  (2019)  Synthesis of Unsymmetrical Aromatic Azoxy Compounds by Silver-Mediated Oxidative Coupling of Aromatic Amines with Nitrosoarenes.  ADVANCED SYNTHESIS & CATALYSIS,  361  (6): (1394-1399).  [10.1002/adsc.201801175]
26. Liangliang He, Jinjin Xu, Qi Wang, Yezi Zhang, Zifei Qin, Yang Yu, Zhengming Qian, Zhihong Yao, Xinsheng Yao.  (2018)  Glucuronidation of [6]-shogaol, [8]-shogaol and [10]-shogaol by human tissues and expressed UGT enzymes: identification of UGT2B7 as the major contributor.  RSC Advances,  8  (72): (41368-41375).  [PMID:35559294] [10.1039/C8RA08466A]
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30. Li Wang, Xiaodan Hong, Zhihong Yao, Yi Dai, Guoping Zhao, Zifei Qin, Baojian Wu, Frank J. Gonzalez, Xinsheng Yao.  (2018)  Glucuronidation of icaritin by human liver microsomes, human intestine microsomes and expressed UDP-glucuronosyltransferase enzymes: identification of UGT1A3, 1A9 and 2B7 as the main contributing enzymes.  XENOBIOTICA,  [PMID:28443723] [10.1080/00498254.2017.1323139]
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32. Zhihong Yao, Shishi Li, Zifei Qin, Xiaodan Hong, Yi Dai, Baojian Wu, Wencai Ye, Frank J. Gonzalez, Xinsheng Yao.  (2017)  Characterization of human UDP-glucuronosyltransferases responsible for glucuronidation and inhibition of norbakuchinic acid, a primary metabolite of hepatotoxicity and nephrotoxicity component bakuchiol in Psoralea corylifolia L..  RSC Advances,  7  (83): (52661-52671).  [10.1039/C7RA10376J]
33. Hai-Chao Huang, Zong-Jun Li, Bin Wang, Xiaolu Chen, Yue-Sheng Li.  (2017)  Synthesis of lactide/ɛ-caprolactone quasi-random copolymer by using rationally designed mononuclear aluminum complexes with modified β-ketiminato ligand.  JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY,  56  (2): (203-212).  [10.1002/pola.28886]
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19. Xing Han, Yang Jing, Ren Kaidi, Qin Zifei, Wang Peile, Zhang Xiaojian, Yao Zhihong, Gonzalez Frank J, Yao Xinsheng.  (2020)  Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu-gu-zhi) and its potential inhibition against human cytochrome P450s and UDP-glucuronosyltransferases.  JOURNAL OF PHARMACY AND PHARMACOLOGY,  72  (12): (1865-1878).  [PMID:32750744] [10.1111/jphp.13337]
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27. Lili Wu, Yulian Chen, Han Liu, Zhikun Zhan, Zhi Liang, Tao Zhang, Zheng Cai, Ling Ye, Menghua Liu, Jie Zhao, Shuwen Liu, Lan Tang.  (2018)  Emodin-induced hepatotoxicity was exacerbated by probenecid through inhibiting UGTs and MRP2.  TOXICOLOGY AND APPLIED PHARMACOLOGY,  359  (91).  [PMID:30248416] [10.1016/j.taap.2018.09.029]
28. Dandan Song, Di Li, Xuan Xiao, Chen Cheng, Somboon Chaemchuen, Ye Yuan, Francis Verpoort.  (2018)  Synthesis of β-oxopropylcarbamates in a recyclable AgBr/ionic liquid catalytic system: An efficient assembly of CO2 under ambient pressure.  Journal of CO2 Utilization,  27  (217).  [10.1016/j.jcou.2018.07.021]
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