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青蒿素

44篇引用文献
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货号 (SKU) 包装规格 是否现货 价格 数量
A110205-20mg
 20mg 现货 Stock Image
A110205-100mg
 100mg 现货 Stock Image
A110205-500mg
 500mg 现货 Stock Image
A110205-1g
 1g 现货 Stock Image
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main product photo

基本描述

别名 黄花蒿素
英文别名 HMS3413P13 | KBioGR_000982 | NSC 369397 | AS-12692 | AKOS024457231 | HMS3713D17 | IDI1_000656 | Artemisininum | BDBM50088447 | MLS001304036 | Prestwick2_000498 | SMR000578089 | Spectrum_001351 | SR-01000802560-2 | quinghaosu | SPBio_002316 | Spectrum2_001
规格或纯度 Moligand™, 分析标准品
英文名称 Artemisinin
运输条件 常规运输

关联靶点（人）

CYP2B6 Tchem 细胞色素 P450 2B6(Cytochrome P450 2B6) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
HMGCR Tclin HMG-CoA reductase (2475 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TOP1 Tclin DNA topoisomerase I (7553 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DHODH Tclin Dihydroorotate dehydrogenase (2737 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2A6 Tchem Cytochrome P450 2A6 (2861 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A-375 (9258 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Breast carcinoma cell (217 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Caco-2 (12174 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CAKI-2 (27 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CCRF-CEM (65223 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
COLO 205 (50209 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
K562 (73714 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MRC5 (9203 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PC-3 (62116 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SH-SY5Y (11521 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
THP-1 (11052 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
U-87 MG (3946 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
WI-38 (2654 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADR5000 cell line (115 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A-431 (6446 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HCT-116 (91556 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HEK293 (82097 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HEp-2 (3859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HFF (3142 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HepG2 (196354 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Melanoma cell line (83 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A2780 (11979 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ovarian cancer cell line (109 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HUVEC (11049 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KB (17409 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HeLa (62764 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BT-549 (31254 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HCT-15 (51914 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SMMC-7721 (5516 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SK-N-AS (237 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SK-N-DZ (143 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ABCC4 Tchem Multidrug resistance-associated protein 4 (785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BEAS-2B (690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L02 (4864 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mycobacterium tuberculosis (203094 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Leishmania donovani (89745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Leishmania major (2877 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Trypanosoma cruzi (99888 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Toxoplasma gondii (4585 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium berghei (192651 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium yoelii (6656 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Human betaherpesvirus 5 (5122 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium yoelii nigeriensis (1119 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Trypanosoma brucei rhodesiense (7991 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PC-12 (7051 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Vero (26788 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L6 (7924 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hemozoin (239 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cysteine protease falcipain-3 (47 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Falcipain 2 (539 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Blood (6 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasma (328 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Chorioallantoic membrane (375 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DHODH Dihydroorotate dehydrogenase (fumarate) (195 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

分子类型 小分子
IUPAC Name (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one
INCHI InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChi Key BLUAFEHZUWYNDE-NNWCWBAJSA-N
Canonical SMILES CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
Isomeric SMILES C[C@@H]1CC[C@H]2[C@H](C(=O)O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)C
WGK Germany 2
RTECS KD4170000
PubChem CID 68827
分子量 282.33
Reaxy-Rn 4194670

化学和物理性质

溶解性 Soluble in methanol, ethanol (24 mg/ml) at 25 °C, DMF, DMSO (57 mg/ml) at 25 °C, acetone, chloroform (25 mg/ml), dichloromethane, and ethyl acetate; almost insoluble in water.
密度 1.24
比旋光度 75 ° (C=0.5, MeOH)
熔点 156-157°C
分子量 282.330 g/mol
XLogP3 2.800
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 282.147 Da
单同位素质量Monoisotopic Mass 282.147 Da
拓扑极表面积Topological Polar Surface Area 54.000 Ų
重原子数Heavy Atom Count 20
形式电荷Formal Charge 0
复杂度Complexity 452.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 7
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

WGK Germany 2
RTECS KD4170000
Reaxy-Rn 4194670
Merck Index 817
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

 SDS英文版

质量标准

Melting point 151-155（℃）
Purity(HPLC) 98-100（%）
Specific Rotation [a]20/D(c=0.5 MeOH) 70-80（°）
Appearance（A110205) White to Off-White Powder or Crystals
Solubility in CHCL3，Colorless,Clear,25mg/ml pass

 质量标准

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到10个结果

批号(Lot Number) 证书类型 日期 货号
E2521063 分析证书 25-06-02 A110205
K2208031 分析证书 24-08-22 A110205
K2208033 分析证书 24-08-22 A110205
K2208034 分析证书 24-08-22 A110205
K2208035 分析证书 24-08-22 A110205
K2119187 分析证书 23-08-15 A110205
K2119188 分析证书 23-08-15 A110205
K2119186 分析证书 23-08-15 A110205
B2318441 分析证书 22-08-27 A110205
G2003140 分析证书 22-04-27 A110205

此产品的引用文献

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1. Jingjing Zhen, Faguang Ma, Rongxin Lin, Ming Yan, Yilin Wu.  (2024)  Porous MOFs-based self-assembled membrane with specific rebinding nanocages for selective recognition and separation at molecular level.  DESALINATION,  572  (117124).  [10.1016/j.desal.2023.117124]
2. Weibai Bian, Ruixuan Zhang, Xiaohui Chen, Chuanxun Zhang, Minjia Meng.  (2023)  Three-Dimensional Porous PVDF Foam Imprinted Membranes with High Flux and Selectivity toward Artemisinin/Artemether.  MOLECULES,  28  (21): (7452).  [PMID:37959871] [10.3390/molecules28217452]
3. Huihui Liu, Qing Wang, Jingru Guo, Kai Feng, Yiling Ruan, Zhihao Zhang, Xin Ji, Jigang Wang, Tao Zhang, Xiaolian Sun.  (2023)  Prodrug-based strategy with a two-in-one liposome for Cerenkov-induced photodynamic therapy and chemotherapy.  JOURNAL OF CONTROLLED RELEASE,  364  (206).  [PMID:37884209] [10.1016/j.jconrel.2023.10.036]
4. Kaicheng Zhang, Rongxin Lin, Ming Yan, Yilin Wu.  (2023)  Click-chemistry synergic MXene-functionalized flexible skeleton membranes for accurate recognition and separation.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  652  (2005).  [PMID:37690308] [10.1016/j.jcis.2023.09.028]
5. Wei-guang Yang, Ao Sun, Rong Zhu, Nan Liu, Wei-jie He, Lin-lin Liu.  (2023)  Exploration of Artemisinin Against IgA Nephropathy via AKT/Nrf2 Pathway by Bioinformatics and Experimental Validation.  Drug Design Development and Therapy,  [PMID:37309415] [10.2147/DDDT.S403422]
6. Minjia Meng, Yi Li, Hui Peng, Binrong Li, Chuanxun Zhang, Jiajia Ren, Qingluola Ren, Yan Liu, Jianming Pan.  (2023)  Hydrophilic imprinted MnO2 nanowires “coating” membrane with ultrahigh adsorption capacity for highly selective separation of Artemisinin/Artemether.  CHEMICAL ENGINEERING JOURNAL,  466  (143020).  [10.1016/j.cej.2023.143020]
7. Wang Qiaolin, Xu Lihe, Qin Zhengbo, Yang Xinyan, Zheng Xianfeng.  (2023)  Potential use of LIAD time-of-flight mass spectrometry for the detection of biomolecules: An example of detecting nucleobases in DNA.  AIP Advances,  13  (3): [10.1063/5.0137046]
8. Jing Yan, Kaicheng Zhang, Faguang Ma, Hang Cui, Yilin Wu.  (2023)  Scalable basswood-based PDA/GO-embedded self-assembly membrane within multilayered artemisinin-imprinted nanocage for high-selectivity cascading adsorption and transport.  CHEMICAL ENGINEERING JOURNAL,  462  (142277).  [10.1016/j.cej.2023.142277]
9. Cunhao Du, Lixiao Ni, Jakpa Wizi, Wenlu Sang, Shiyi Rong, Xianglan Li, Chu Xu, Yan Li, Xuqing Chen, Shiyin Li.  (2023)  The inhibition mechanism and death mode of Microcystis aeruginosa induced by the continuous pressure of artemisinin sustained-release microspheres (ASMs).  Algal Research-Biomass Biofuels and Bioproducts,  71  (103031).  [10.1016/j.algal.2023.103031]
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14. Yang Jinlan, Gao Yulan, Yang Li.  (2022)  Capillary-based fluorescence microsensor with polyoxometalates as nanozyme for rapid and ultrasensitive detection of artemisinin.  MICROCHIMICA ACTA,  189  (1): (1-8).  [PMID:34964917] [10.1007/s00604-021-05126-z]
15. Sennan Qiao, Hansi Zhang, Fei Sun, Zhenyan Jiang.  (2021)  Molecular Basis of Artemisinin Derivatives Inhibition of Myeloid Differentiation Protein 2 by Combined in Silico and Experimental Study.  MOLECULES,  26  (18): (5698).  [PMID:34577169] [10.3390/molecules26185698]
16. Qing Wang, Naijie Wei, Jingru Guo, Kai Feng, Yin Kwan Wong, Jingwei Zhang, Jigang Wang, Xiaolian Sun.  (2021)  Hemin-lipid assembly as an artemisinin oral delivery system for enhanced cancer chemotherapy and immunotherapy.  Nanoscale,  13  (31): (13231-13240).  [PMID:34477731] [10.1039/D1NR01302E]
17. Yan Peng, Yan Ma, Yu Bao, Zulan Liu, Li Chen, Fangyin Dai, Zhi Li.  (2021)  Electrospun PLGA/SF/artemisinin composite nanofibrous membranes for wound dressing.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  183  (68).  [PMID:33892031] [10.1016/j.ijbiomac.2021.04.021]
18. Li Zihaoran, Wu Xinghan, Wang Wenyu, Gai Chengcheng, Zhang Weifen, Li Wentong, Ding Dejun.  (2021)  Fe(II) and Tannic Acid-Cloaked MOF as Carrier of Artemisinin for Supply of Ferrous Ions to Enhance Treatment of Triple-Negative Breast Cancer.  Nanoscale Research Letters,  16  (1): (1-11).  [PMID:33620584] [10.1186/s11671-021-03497-z]
19. Xinyi Wang, Yiwei Xie, Ning Jiang, Jingyi Wang, Hongrui Liang, Dingyuan Liu, Na Yang, Xiaoyu Sang, Ying Feng, Ran Chen, Qijun Chen.  (2021)  Enhanced Antimalarial Efficacy Obtained by Targeted Delivery of Artemisinin in Heparin-Coated Magnetic Hollow Mesoporous Nanoparticles.  ACS Applied Materials & Interfaces,  13  (1): (287–297).  [PMID:33356111] [10.1021/acsami.0c20070]
20. Longkai Yang, Qiu Xiong, Yanbo Li, Peng Gao, Ben Xu, Hong Lin, Xin Li, Tsutomu Miyasaka.  (2021)  Artemisinin-passivated mixed-cation perovskite films for durable flexible perovskite solar cells with over 21% efficiency.  Journal of Materials Chemistry A,  9  (3): (1574-1582).  [10.1039/D0TA10717D]
21. Yulan Gao, Miaomiao Tian, Yaxue Jia, Xiaohong Wang, Li Yang.  (2021)  Polyoxometalates as catalysts for fluorescence amplification in rapid and sensitive detection of artemisinin.  ANALYTICA CHIMICA ACTA,  1143  (101).  [PMID:33384107] [10.1016/j.aca.2020.11.035]
22. Mengqi Bai, Li Qiang, Minjia Meng, Binrong Li, Suao Wang, Yilin Wu, Li Chen, Jiangdong Dai, Yan Liu, Jianming Pan.  (2021)  Upper surface imprinted membrane prepared by magnetic guidance phase inversion method for highly efficient and selective separation of Artemisinin.  CHEMICAL ENGINEERING JOURNAL,  405  (126899).  [10.1016/j.cej.2020.126899]
23. Yingying Cao, Yongqiang Zhang, Ying Zhang, Ling Wang, Lunchao Lv, Xifei Ma, Shaojuan Zeng, Hui Wang.  (2020)  Biodegradable functional chitosan membrane for enhancement of artemisinin purification.  CARBOHYDRATE POLYMERS,  246  (116590).  [PMID:32747249] [10.1016/j.carbpol.2020.116590]
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